Gene Information

Gene Summary

Gene Symbol:GAPDH
refSeq:NM_001256799
kgID:uc031qfw.1
spID:P04406
spDisplayID:G3P_HUMAN
Description:Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), transcript variant 2, mRNA.
Summary:The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

Disease Information

MIM:138400
Gene(s):
Disorder(s):
Cytogenetic location:

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Genomic Context

Genomic Location:chr12:6644408-6647537
Chromosome:chr12
Strand:+
Transcript Length:3129
Transcription Start:6644408
Transcription End:6647537
5' UTR Length:1348
CDS Length:1580
CDS Start:6645756
CDS End:6647336
3' UTR Length:201
Exon Count:8

gRNAs

Sequence Information

Notes

References

Jaskula-Ranga, V and Zack, DJ. 2016. grID: A CRISPR-Cas9 guide RNA Database and Resource for Gene-Editing.

bioRxiv 097352; doi: https://doi.org/10.1101/097352

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